Science

A subcutaneous enzyme replacement therapy with affinity for bone that is currently in clinical trials.ENB-0040 is an investigational product currently being studied as an A molecule that catalyzes or triggers biochemical reactions.enzyme replacement therapy in phase II
A research study that uses consenting human subjects to test the safety and efficacy of new therapeutic interventions and diagnostic tests.clinical trials for the treatment of A rare, inherited, and sometimes fatal metabolic bone disease characterized by poor bone mineralization and profound skeletal defects.hypophosphatasia. It is an engineered form of the key enzyme that HPP patients lack, and is designed to have a high affinity for bone. Nonclinical mouse studies showed that ENB-0040 has exhibited pre-clinical activity in the treatment of HPP. Clinical studies are ongoing.