Enobia develops therapies to treat serious The biological unit of heredity that is made up of a DNA sequence, occupies a precise location (locus) on a chromosome, and contains instructions for the production of a particular protein.genetic bone disorders for which there are no approved treatments. Our lead product, A subcutaneous enzyme replacement therapy with affinity for bone that is currently in clinical trials.ENB-0040 (human recombinant tissue non-specific alkaline phosphatase), is a subcutaneous bone-targeted A molecule that catalyzes or triggers biochemical reactions.enzyme replacement therapy for A rare, inherited, and sometimes fatal metabolic bone disease characterized by poor bone mineralization and profound skeletal defects.hypophosphatasia and is currently in Phase 2 clinical studies.
A rare, inherited, and sometimes fatal metabolic bone disease characterized by poor The process by which the body uses minerals to build bone structure.bone mineralization and profound skeletal defects.Hypophosphatasia is a rare genetic skeletal dysplasia characterized by skeletal Relating to a deficiency of minerals.hypomineralization. Symptoms include failure to thrive, respiratory insufficiency, A softening of bones in children leading to fractures and deformity, which is predominantly caused by a vitamin D deficiency.rickets, myopathy and seizures in infants; rickets, myopathy, poor growth, non-traumatic fractures and early loss of primary teeth in children; and The adult form of rickets, which is a softening of the bones caused by defective bone mineralization.osteomalacia or "soft bones", frequent non-traumatic fractures, bone pain and early permanent tooth loss in adults.