Company

Enobia develops therapies to treat serious The biological unit of heredity that is made up of a DNA sequence, occupies a precise location (locus) on a chromosome, and contains instructions for the production of a particular protein.genetic bone disorders for which there are no approved treatments. Our lead product, A subcutaneous A molecule that catalyzes or triggers biochemical reactions.enzyme replacement therapy with affinity for bone that is currently in A research study that uses consenting human subjects to test the safety and efficacy of new therapeutic interventions and diagnostic tests.clinical trials.A subcutaneous A medical treatment that replaces an enzyme in patients who either lack or have a deficient form of the particular enzyme.enzyme replacement therapy with affinity for bone that is currently in clinical trials.A subcutaneous enzyme replacement therapy with affinity for bone that is currently in clinical trials.ENB-0040 (human recombinant tissue non-specific alkaline phosphatase), is a subcutaneous bone-targeted enzyme replacement therapy for A rare, inherited, and sometimes fatal metabolic bone disease characterized by poor bone mineralization and profound skeletal defects.hypophosphatasia and is currently in Phase 2 clinical studies.

A rare, inherited, and sometimes fatal metabolic bone disease characterized by poor The process by which the body uses minerals to build bone structure.bone mineralization and profound skeletal defects.Hypophosphatasia is a rare genetic skeletal dysplasia characterized by skeletal Relating to a deficiency of minerals.hypomineralization. Symptoms include failure to thrive, respiratory insufficiency, A softening of bones in children leading to fractures and deformity, which is predominantly caused by a vitamin D deficiency.rickets, myopathy and seizures in infants; rickets, myopathy, poor growth, non-traumatic fractures and early loss of primary teeth in children; and The adult form of rickets, which is a softening of the bones caused by defective bone mineralization.osteomalacia or "soft bones", frequent non-traumatic fractures, bone pain and early permanent tooth loss in adults.